Assessing vascular permeability during experimental cerebral malaria by a radiolabeled monoclonal antibody technique.

نویسندگان

  • H C van der Heyde
  • P Bauer
  • G Sun
  • W L Chang
  • L Yin
  • J Fuseler
  • D N Granger
چکیده

Vascular endothelial integrity, assessed by Evans blue dye extrusion and radiolabeled monoclonal antibody leakage, was markedly compromised in the brain, lung, kidney, and heart during Plasmodium berghei infection, a well-recognized model for human cerebral malaria. The results for vascular permeability from both methods were significantly (P < 0.001) related.

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عنوان ژورنال:
  • Infection and immunity

دوره 69 5  شماره 

صفحات  -

تاریخ انتشار 2001